Planar-bilayer activities of linear oligoester bolaamphiphiles

• Jonathan K. W. Chui,
• Thomas M. Fyles and
• Horace Luong

Beilstein J. Org. Chem. 2011, 7, 1562–1569, doi:10.3762/bjoc.7.184

• voltage-dependent. The varied and irregular activities were summarized with the aid of a recently developed “activity-grid” method. Keywords: activity grid; single-molecule studies; synthetic ion channels; voltage clamp experiment; Introduction Ion channels modulate conductance in cell membranes, and

• investigation along these lines will be necessary to advance our understanding of how these simple channels “work”. The second conclusion concerns the “what compounds ought we to think about” question. Many synthetic ion channels require heroic synthetic efforts, and one of the enduring motivations in various